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Rabbit Anti-AQP2
Catalog Number : HZ323213 Quantity size : 0.1ml （dilute with pH
7.4 0.01 M PBS or antibody diluent ）
Background: Aquaporins （AQPs） are a large family of integral membrane water
transport channel proteins that facilitate the transport of water through the cell mem-
brane. This function is conserved in animals, plants and bacteria. Many isoforms of
aquaporin have been identified in mammals, designated AQP0 through AQP10.
Aquaporins are widely distributed and it is not uncommon for more than one type of
AQP to be present in the same cell. Although most aquaporins are only permeable to
water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable
to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin
to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved
in renal water absorption, generation of pulmonary secretions, lacrimation and the
secretion and reabsorption of cerebrospinal fluid and aqueous humor. AQP1 is an
integral membrane protein expressed in erythrocytes and renal tubule cells.
pecificity :
– Anti-AQP2 is a rabbit polyclonal antibody unconjugated
– specific for AQP2 of human, mouse, rat
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– Protein A affinity chromatography purification, purity :>95%
– Isotype: IgG
– mol wt: 29kDa
Application :
– Western blotting 1:100-500
– Immunohistochemistry 1:100-500
– ELISA 1:500-1000
– Optimal working dilutions must be determined by the end user.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The
lyophilized antibody is stable at room temperature for at least one month and for
greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M
PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for
use in human, therapeutic or diagnostic applications.
